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Cognitive function is a key determinant of independence and quality of life among older adults. Compared to adults in England, US adults have a greater prevalence of cardiovascular risk factors and disease tha...
Functional disability, the loss of ability to carry out daily tasks unaided, is a major adverse outcome more common with increasing age. The potential contribution of neuropathological changes in subcortical a...
Care for people with dementia and their informal caregivers is a challenging aim in healthcare. There is an urgent need for cost-effective support programs that prevent informal caregivers of people with demen...
While antidepressant-induced suicidality is a concern in younger age groups, there is mounting evidence that these drugs may reduce suicidality in the elderly. Regarding a possible association between other ty...
An attenuation of the insulin-like growth factor 1 (IGF-1) signaling has been associated with elongation of the lifespan in simple metazoan organisms and in rodents. In humans, IGF-1 level has an age-related m...
The use of psychotropic medications and their adverse effects in frail elderly has been debated extensively. However, recent data from European studies show that these drugs are still frequently prescribed in ...
5.8 M living Americans have experienced a stroke at some time in their lives, 780K had either their first or a recurrent stroke this year, and 150K died from strokes this year. Stroke costs about $66B annually...
Information on hypertension in the very elderly is sparse. Until recently evidence of benefits from pharmacological treatment was inconclusive. We estimated the prevalence of hypertension in subjects aged 80 o...
Motor learning research has had little impact on clinical applications and rarely extended to research about how older adults learn motor skills. There is consistent evidence that motor skill performance and l...
Accidental falls by older patients in hospital are one of the most commonly reported adverse events. Falls after discharge are also common. These falls have enormous physical, psychological and social conseque...
Falls remain a major public health problem, despite strong growth in the research evidence of effective single and multifactorial interventions, particularly in the community setting. A number of aspects of fa...
Brain size is associated with cognitive ability in adulthood (correlation ~ .3), but few studies have investigated the relationship in normal ageing, particularly beyond age 75 years. With age both brain size ...
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 9 Supplement 1
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