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Table 4 Diagnostic test evaluation of sarcopenia screening tools

From: A comparative analysis of sarcopenia screening methods in Thai people with type 2 diabetes mellitus in an outpatient setting

Parameters

Sensitivity

(95%CI)

Specificity

(95%CI)

PPV

(95%CI)

NPV

(95%CI)

LR + 

(95%CI)

LR-

(95%CI)

Accuracy

(95%CI)

AUC

(95%CI)

Calf circumference

(M < 34 cm; F < 33 cm)

59.0a,b

(47.3, 70.0)

92.4a,b,c

(88.4, 95.4)

70.8

(58.2, 81.4)

87.9

(83.3, 91.6)

7.79

(4.87, 12.47)

0.44

(0.34, 0.58)

84.5

(80.1, 88.2)

0.8921,2,3,4,5,6,7

(0.857, 0.927)

Neck circumference

(M < 38 cm; F < 32.8 cm)

33.3c,d,e

(23.1, 44.9)

94.8d,e,f

(91.3, 97.2)

66.7

(51.9, 78.7)

82.1

(79.6, 84.3)

6.44

(3.48, 11.91)

0.70

(0.60, 0.82)

80.2

(75.5, 84.4)

0.7851,8,9,10,11

(0.728, 0.841)

SARC-F (≥ 4)

25.6a,f,g,h

(16.4, 36.8)

86.1 h,i,j

(81.1, 90.1)

36.4

(26.0, 48.2)

78.8

(76.4, 81.1)

1.84

(1.13, 2.99)

0.86

(0.75, 0.99)

71.7

(66.5, 76.5)

0.6022,8,12,13,14

(0.529, 0.674)

SARC-CalF (≥ 11)

48.7i,j,k

(37.2, 60.3)

93.2 k,l,m

(89.4, 96.0)

69.1

(57.3, 78.9)

85.4

(82.5, 87.9)

7.19

(4.31, 12.0)

0.55

(0.44, 0.68)

82.7

(78.1, 86.6)

0.7893,12,15,16

(0.727, 0.852)

SARCF + EBM (≥ 12)

35.9 l,m,n

(25.3, 47.6)

87.7n,q,o

(82.9, 91.5)

47.5

(36.7, 58.5)

81.5

(78.7, 83.9)

2.91

(1.87, 4.53)

0.73

(0.62, 0.87)

75.4

(70.4, 79.9)

0.7744,13,17,18

(0.715, 0.834)

Hand grip strength

(M < 28 kg; F < 18 kg)

80.8c,f,I,l

(70.3, 88.8)

55.8a,d,h,k,n,p,r

(49.4, 62.0)

36.2

(32.2, 40.4)

90.3

(85.4, 93.7)

1.83

(1.53, 2.18)

0.34

(0.22, 0.55)

61.7

(56.2, 66.9)

0.7165,9,14,19

(0.652, 0.781)

5-times chair stand

(≥ 12 s)

90.5b,d,g,j,m

(81.5, 96.1)

28.3b,e,i,l,q,p

(22.7, 34.4)

27.7

(25.6, 29.9)

90.8

(82.6, 95.4)

1.26

(1.13, 1.41)

0.33

(0.16, 0.70)

42.8

(37.3, 48.4)

0.6576,10,15,17

(0.588, 0.725)

Gait speed (< 1 m/s)

84.2e,h,k,n

(74.0, 91.6)

27.6c,f,j,m,o,r

(22.2, 33.6)

26.1

(23.8, 28.6)

85.2

(76.7, 90.9)

1.16

(1.03, 1.32)

0.57

(0.33, 1.00)

40.8

(35.4, 46.4)

0.6237,11,16,18,19

(0.548, 0.697)

  1. Identical letters indicate statistically significant differences at the 0.05 level between sensitivity and specificity by the Marascuillo procedure
  2. Identical numbers indicate statistically significant differences at the 0.05 level between the AUC curves by the DeLong test
  3. PPV Positive Predictive Value, NPV Negative Predictive Value, LR + Positive Likelihood Ratio, LR- Negative Likelihood Ratio, AUC Area under the curve