Table 7 Diagnostic properties of T-FRAIL, CFS-Thai and ECOG PS for frailty detection using mTFI as the reference standard
Tool | Cutoff-points | Sensitivity % (95% CI) | Specificity % (95% CI) | AUC (95% CI) | Youden Index | p-value |
|---|---|---|---|---|---|---|
T-FRAIL | ≥ 2 | 70.7 (54.5–83.9) | 80.0 (56.3–94.3) | 0.75 (0.64–0.87) | 50.7 | 0.001 |
T-FRAIL | ≥ 3 | 39.0 (24.2–55.5) | 100.0 (83.2–100.0) | 0.70 (0.62–0.77) | 39.0 | 0.025 |
CFS-Thai | ≥ 4 | 92.7 (80.1–98.5) | 55.0 (31.5–76.9) | 0.74 (0.62–0.86) | 47.7 | < 0.001 |
CFS-Thai | ≥ 5 | 93.5 (79.3–98.2) | 79.3 (61.6–90.2) | 0.86 (0.81–0.92) | 53.5 | < 0.001 |
ECOG PS | ≥ 2 | 83.9 (67.4–92.9) | 93.3 (78.7–98.2) | 0.89 (0.82–0.95) | 42.5 | 0.001 |
ECOG PS | ≥ 3 | 35.5 (21.1–53.1) | 96.7 (83.3–99.4) | 0.67 (0.59–0.76) | 12.5 | < 0.001 |