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Table 2 Associations between HGI with CERAD– WL, CERAD -DR, AFT, and DSST

From: Exploring the association between hemoglobin glycation index and cognitive function in older adults with hypertension: a cross-sectional study

Characteristic

Model 1

Model 2

Model 3

β (95% CI)

β (95% CI)

β (95% CI)

CERAD– WL

   

HGI (continuous)

-0.29 (-0.90, 0.32)

-0.38 (-0.91, 0.15)

-0.32 (-0.74, 0.10)

HGI (categories)

   

 Q1

Reference

Reference

Reference

 Q2

0.47 (-0.66, 1.60)

0.58 (-0.53, 1.70)

0.40 (-0.76, 1.60)

 Q3

0.25 (-0.84, 1.30)

0.38 (-0.61, 1.40)

-0.13 (-1.50, 1.30)

 Q4

-0.41 (-1.40, 0.60)

-0.31 (-1.30, 0.67)

-0.02 (-0.75, 0.70)

CERAD -DR

   

HGI (continuous)

-0.14 (-0.41, 0.12)

-0.19 (-0.44, 0.06)

-0.11 (-0.33, 0.10)

HGI (categories)

   

 Q1

Reference

Reference

Reference

 Q2

0.05 (-0.52, 0.62)

0.11 (-0.45, 0.67)

0.25 (-0.34, 0.83)

 Q3

0.14 (-0.30, 0.57)

0.20 (-0.18, 0.59)

0.01 (-0.55, 0.58)

 Q4

-0.31 (-0.80, 0.17)

-0.27 (-0.72, 0.19)

-0.02 (-0.50, 0.46)

AFT

   

HGI (continuous)

-0.55 (-1.80, 0.71)

-0.65 (-1.70, 0.44)

-0.19 (-1.10, 0.74)

HGI (categories)

   

 Q1

Reference

Reference

Reference

 Q2

0.63 (-0.52, 1.80)

0.75 (-0.31, 1.80)

1.6 (0.14, 3.10)

 Q3

0.25 (-1.40, 1.90)

0.40 (-1.10, 1.90)

0.74(-1.20, 2.60)

 Q4

-1.6 (-3.60, 0.46)

-1.5 (-3.30, 0.37)

-0.40(-2.30, 1.50)

DSST

   

HGI (continuous)

-3.80 (-7.20, -0.28)

-4.20 (-6.90, -1.60)

-2.50 (-4.60, -0.36)

HGI (categories)

   

 Q1

Reference

Reference

Reference

 Q2

0.42 (-2.70, 3.60)

0.94 (-2.00, 3.90)

1.10 (-2.50, 4.80)

 Q3

-1.20 (-4.70, 2.40)

-0.52 (-13.00, -3.90)

0.00 (-3.30, 3.30)

 Q4

-8.90 (-14.00, -3.40)

-8.50 (-13.00, -3.90)

-4.50 (-8.10, -0.88)

  1. Model 1 was adjusted for none
  2. Model 2 was adjusted for age
  3. Model 3 was adjusted for sex, age, race, education level, PIR, BMI, smoking status, alcohol consumption, SBP, DBP, antihypertensive drug use and BP classification
  4. Abbreviation: HGI, hemoglobin glycation index; CERAD-WL/DR, the Consortium to Establish a Registry for Alzheimer’s Disease Word Learning subtest for assessing learning and memory; AFT, the Animal Fluency Test for verbal fluency and DSST, the Digit Symbol Substitution Test; Q, quartile