Fig. 1

*The risk scores for 15 distinct adverse drug reactions (ADR) among 2,387 residents with hyper-polypharmacy (i.e. taking ≥ 10 medications)

*The x-axis represents the 15 types of adverse drug reactions as outlined by the Cumulative Toxicity Tool of the Polypharmacy Guidance 2018, while the y-axis represents the cumulative risk scores. Each square denotes the specific risk score, and the number within each square indicates the number of patients at that risk score level. A darker color indicates a higher number of residents bearing that risk score level

CNS depression: central nervous system depression; CV events: cardiovascular events