Table 9 Relationship between the risk genotypes of rs1800566 SNP and Non-modifiable and modifiable risk factors associated with intrinsic skin aging
Risk factors | Genotype | |||||
|---|---|---|---|---|---|---|
rs1800566 | ||||||
GA or AA carriers | ||||||
Mean difference (I − J) | Std. error | Sig. | 95% confidence interval | |||
Lower bound | Upper bound | |||||
Non-modifiable risk factor | ||||||
Gender | ||||||
Male | 1.46364 | 1.31430 | .267 | -1.1283 | 4.0555 | |
Female | 4.95299a | 1.19105 | .000 | 2.6042 | 7.3018 | |
Age (>35) | 24.2550 | 1.81010 | .000 | 19.6020 | 28.9080 | |
Modifiable risk factors | ||||||
Water intake | ||||||
≥ 8 glass | 3.26756 | 1.71496 | .058 | -.1145 | 6.6496 | |
≤ 5 glass | 4.73783a | 1.84418 | .011 | 1.1010 | 8.3747 | |
Micronutrient Care | ||||||
Yes | .42025 | .24701 | .209 | -.1661 | 1.0066 | |
No | 2.95750a | .24701 | .000 | 2.3711 | 3.5439 | |
Sleeping habits | ||||||
≥ 7 hours | 3.01282 | 1.95939 | .126 | -.8512 | 6.8769 | |
5-7 hours | 2.96818a | .86029 | .001 | 1.2716 | 4.6647 | |
Sun exposure | ||||||
Extensive | 4.15674a | 1.31838 | .002 | 1.5568 | 6.7567 | |
Un-extended | 3.40951a | 1.20134 | .005 | 1.0404 | 5.7786 | |
Application of Sunscreen cream | ||||||
Yes | -1.07866 | 1.11381 | .334 | -3.2752 | 1.1179 | |
No | -3.55821a | 1.06068 | .001 | -5.6500 | -1.4665 | |