Table 8 Relationship between the risk genotypes of rs1051740 SNP and Non-modifiable and modifiable risk factors associated with intrinsic skin aging
Risk factors | Genotype | |||||
|---|---|---|---|---|---|---|
rs1051740 | ||||||
TC or CC carriers | ||||||
Mean difference (I − J) | Std. error | Sig. | 95% confidence interval | |||
Lower bound | Upper bound | |||||
Non-modifiable risk factor | ||||||
Gender | ||||||
Male | 3.48936a | .92556 | .000 | 1.6641 | 5.3146 | |
Female | -1.46364 | 1.31430 | .267 | -4.0555 | 1.1283 | |
Age (>35) | 27.2056 | .46490 | .000 | 26.2828 | 28.1284 | |
Modifiable risk factors | ||||||
Water intake | ||||||
≥ 8 glass | -1.47028 | .98301 | .136 | -3.4089 | .4683 | |
≤ 5 glass | -4.73783a | 1.84418 | .011 | -8.3747 | -1.1010 | |
Micronutrient Care | ||||||
Yes | 2.62500 | 2.07374 | .417 | -2.2979 | 7.5479 | |
No | -2.53725a | .24701 | .000 | -3.1236 | -1.9509 | |
Sleeping habits | ||||||
≥ 7 hours | .04464 | 1.92529 | .982 | -3.7522 | 3.8415 | |
5-7 hours | -2.96818a | .86029 | .001 | -4.6647 | -1.2716 | |
Sun exposure | ||||||
Extensive | -4.15674a | 1.31838 | .002 | -6.7567 | -1.5568 | |
Un-extended | -.74723 | .98270 | .448 | -2.6852 | 1.1907 | |
Application of Sunscreen cream | ||||||
Yes | 1.07866 | 1.11381 | .334 | -1.1179 | 3.2752 | |
No | -2.47955a | .99944 | .014 | -4.4505 | -.5086 | |