Table 7 Relationship between the risk genotypes of rs2234922 SNP and Non-modifiable and modifiable risk factors associated with intrinsic skin aging
Risk factors | Genotype | |||||
|---|---|---|---|---|---|---|
rs2234922 | ||||||
AG or GG carriers | ||||||
Mean difference (I − J) | Std. error | Sig. | 95% confidence interval | |||
Lower bound | Upper bound | |||||
Non-modifiable risk factor | ||||||
Gender | ||||||
Male | -3.48936a | .92556 | .000 | -5.3146 | -1.6641 | |
Female | -4.95299a | 1.19105 | .000 | -7.3018 | -2.6042 | |
Age (>35) | 26.1184 | .42002 | .000 | 25.2846 | 26.9521 | |
Modifiable risk factors | ||||||
Water intake | ||||||
≥ 8 glass | 1.47028 | .98301 | .136 | -.4683 | 3.4089 | |
≤ 5 glass | -3.26756a | 1.71496 | .049 | -6.6496 | .1145 | |
Micronutrient Care | ||||||
Yes | 3.35000 | 1.89700 | .186 | -1.1533 | 7.8533 | |
No | 6.52425a | 1.13781 | .000 | 3.8232 | 9.2253 | |
Sleeping habits | ||||||
≥ 7 hours | -.04464 | 1.92529 | .982 | -3.8415 | 3.7522 | |
5-7 hours | -3.01282 | 1.95939 | .126 | -6.8769 | .8512 | |
Sun exposure | ||||||
Extensive | -3.40951a | 1.20134 | .005 | -5.7786 | -1.0404 | |
Un-extended | .74723 | .98270 | .448 | -1.1907 | 2.6852 | |
Application of Sunscreen cream | ||||||
Yes | 2.47955a | .99944 | .014 | .5086 | 4.4505 | |
No | 3.55821a | 1.06068 | .001 | 1.4665 | 5.6500 | |