Effects of sarcopenia on postoperative recovery in elderly patients after cardiac surgery with cardiopulmonary bypass

Table 3 Prognostic utility of sarcopenia in predicting postoperative complications

Variables	Univariate analysis		Multivariate analysis
Variables	OR (95%CI)	P	OR (95%CI)	P
Age, y	1.030 (0.971–1.093)	0.330
Male, n (%)	1.913 (1.084–3.375)	0.025	1.925 (0.818–4.531)	0.134
BMI (kg/m ²)	0.962 (0.891–1.038)	0.321
Concomitant diseases, n (%)
Diabetes	1.704 (0.752–3.858)	0.201
Hypertension	0.620 (0.351–1.096)	0.100
COPD	1.603(0.143–17.976)	0.702
Cerebrovascular disease	2.221 (0.912–5.405)	0.079
NYHA ≧ 3, n (%)	1.318 (0.751–2.314)	0.336
CONUT ≧ 2, n (%)	2.450 (1.272–4.717)	0.007	0.908 (0.799–1.031)	0.137
Preoperative laboratory tests
Serum albumin, g/dL	0.824 (0.744–0.913)	< 0.001	0.896 (0.790–1.017)	0.090
Triglyceride, mmol/L	0.864 (0.589–1.268)	0.456
LDL-C, mmol/L	0.934 (0.654–1.333)	0.705
HDL-C, mmol/L	0.613 (0.275–1.369)	0.233
Creatinine, mg/dL	1.021 (1.008–1.034)	0.002	1.005 (0.983–1.027)	0.677
eGFR, mL/min/1.73 m²	0.983 (0.972–0.995)	0.005	0.990 (0.969–1.011)	0.346
Hemoglobin, g/L	0.988 (0.972–1.004)	0.142
WBC, ×10 ⁹/L	1.100 (1.010–1.198)	0.028	1.098(0.991–1.217)	0.074
Lymphocytes, ×10⁹/L	0.523 (0.310–0.883)	0.015	0.738(0.375–1.454)	0.380
Type of surgery, n (%)
Valve	Reference
Valve + aorta	2.689 (1.297–5.573)	0.008	1.273 (0.491-3.300)	0.620
Valve + Other	1.618 (0.831–3.151)	0.157	0.940 (0.396–2.231)	0.889
Intraoperative time, min
Surgical time	1.011 (1.007–1.015)	< 0.001	1.008 (1.001–1.015)	0.023
CPB time	1.018 (1.012–1.025)	< 0.001
Aortic cross-clamp time	1.019 (1.011–1.026)	< 0.001	1.009 (0.998–1.020)	0.112
Sarcopenia
No	Reference
Yes	2.626 (1.447–4.766)	0.002	2.457 (1.178–5.126)	0.017

Note: BMI, body mass index; COPD, chronic obstructive pulmonary disease; NYHA, New York heart association; CONUT, Controlling Nutritional Status; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate; WBC, white blood cell count; CPB, cardiopulmonary bypass

ISSN: 1471-2318