Table 1 The characteristics of the enrolled subjects
From: Dyrk1b as a potential biomarker for sarcopenia in older adults
Variables | Non-Sarcopenia (n = 401) | Sarcopenia (n = 538) | P |
|---|---|---|---|
Age, years | 76.0 (71.0–80.0) | 77.0 (70.0–82.0) | 0.037 |
Male, n (%) | 230 (57.4) | 294 (54.6) | 0.408 |
BMI, kg/m2 | 25.17 (23.06–26.94) | 22.35 (20.00-23.92) | < 0.001 |
Smokers, n (%) | 60 (15.0) | 71 (13.2) | 0.440 |
Drinkers, n (%) | 45 (11.2) | 50 (9.3) | 0.332 |
Hypertension, n (%) | 192 (47.9) | 238 (44.2) | 0.268 |
Diabetes, n (%) | 50 (12.5) | 105 (19.5) | 0.004 |
FBG, mmol/L | 5.47 (5.10–6.11) | 5.63 (5.19–6.53) | 0.002 |
ALT, U/L | 16.18 (12.33–21.31) | 15.07 (11.06–20.18) | 0.006 |
AST, U/L | 21.38 (19.00–26.00) | 22.00 (18.52-27.00) | 0.183 |
TBil, µmol/L | 13.13 (10.93–16.90) | 12.28 (9.50-15.94) | < 0.001 |
SCr, µmol/L | 72.00 (53.50-85.57) | 66.53 (51.86–83.55) | 0.074 |
BUN, mmol/L | 5.63 (4.59–6.44) | 5.47 (4.60–6.97) | 0.083 |
TC, mmol/L | 4.74 (4.13–5.39) | 4.93 (4.27–5.48) | 0.002 |
TG, mmol/L | 1.41 (1.04–1.95) | 1.12 (0.89–1.60) | < 0.001 |
LDL-C, mmol/L | 2.40 (1.88–2.78) | 2.47 (1.88–3.08) | 0.022 |
HDL-C, mmol/L | 1.37 (1.21–1.56) | 1.47 (1.24–1.74) | < 0.001 |
Dyrk1b, pg/mL | 70.40 (58.34–92.35) | 67.37 (55.13–82.56) | 0.008 |
Grip, kg | 28.10 (22.50–33.90) | 17.90 (15.50-24.83) | < 0.001 |
Gait speed, m/s | 1.05 (0.96–1.14) | 0.95 (0.80–1.09) | < 0.001 |
ASMI, kg/m2 | 7.10 (6.46–7.70) | 5.62 (5.13–6.50) | < 0.001 |