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Table 2 Univariate comparisons of clinical parameters, including admission NHFS and selected inflammatory biomarkers, with postoperative outcomes

From: Association between markers of inflammation and outcomes after hip fracture surgery: analysis of routinely collected electronic healthcare data

 

Alive at 30 days N = 970

Died within 30 days N = 69

p

LOS < 28 days* N = 699

LOS ≥ 28 days* N = 269

p

Returned home within 30 days* N = 452

Did not return home within 30 days* N = 283

p

Mean NHFS (SD)

4.9 (1.5)

5.9 (1.4)

< 0.001a

4.8 (1.5)

5.2 (1.4)

< 0.001a

4.2 (1.3)

5.0 (1.2)

< 0.001a

Mean albumin, g/L (SD)

39 (4)

35 (5)

< 0.001a

39 (4)

38 (4)

0.006a

40 (4)

38 (5)

< 0.001a

Median CRP, mg/L (IQR)

7 (2–27)

14 (6–53)

0.002b

7 (2–24)

8 (3–36)

0.087b

5 (2–20)

8 (3–30)

0.036b

Median NLR (IQR)

9.0 (5.7–13.9)

10.3 (7.1–15.8)

0.086b

8.8 (5.5–13.2)

9.6 (6.4–15.9)

0.001b

9.09 (5.7–13.4)

9.9 (6.5–16.3)

0.002b

Median MLR (IQR)

0.7 (0.5–1.0)

0.8 (0.5–1.2)

0.055b

0.6 (0.5–1.0)

0.7 (0.5–1.1)

0.026b

0.7 (0.5–1.0)

0.7 (0.5–1.1)

0.037b

  1. NHFS: Nottingham Hip Fracture Score; CRP: C-reactive protein; NLR: Neutrophil-to-lymphocyte ratio; MLR: Monocyte-to-lymphocyte ratio. IQR, interquartile range; SD, standard deviation. p-value using (a) One-way ANOVA and (b) Mann-Whitney U test. Significant results are highlighted in bold. *Analysis of hospital LOS and postoperative discharge destination at 30 days excluded any patients who died within this period. Analysis of postoperative discharge destination at 30 days only included patients admitted from their own homes or sheltered housing