Intrinsic capacity trajectories and cardiovascular disease incidence among Chinese older adults: a population-based prospective cohort study

Table 4 Subgroup analysis of hazard ratio of CVD among older adults according to IC trajectories

	High IC with Subsequent Decline	Moderate IC with Subsequent Increase	Low IC with Slow Decline	p for interaction
Gender				0.590
Male
Case/Total	84/250	337/994	169/405
HR	1 (reference)	1.16 (0.89, 1.49)	1.59 (1.19, 2.13)
Female
Case/Total	83/197	379/878	299/612
HR	1 (reference)	1.14 (0.89, 1.45)	1.72 (1.32, 2.25)
Age				0.277
60–69
Case/Total	146/401	554/1 439	287/586
HR	1 (reference)	1.16 (0.96, 1.39)	1.71 (1.38, 2.13)
70–79
Case/Total	21/44	153/408	160/382
HR	1 (reference)	0.98 (0.60, 1.59)	1.34 (0.81, 2.21)
≥ 80
Case/Total	0/2	9/25	21/49
HR	1 (reference)	/	/
Hypertension				0.403
Yes
Case/Total	63/135	320/578	207/340
HR	1 (reference)	1.47 (1.11, 1.94)	2.05 (1.50, 2.80)
No
Case/Total	104/311	396/1 287	260/671
HR	1 (reference)	0.96 (0.77, 1.21)	1.43 (1.11, 1.84)
Diabetes				0.649
Yes
Case/Total	15/31	80/128	47/73
HR	1 (reference)	1.51 (0.84, 2.70)	2.53 (1.27, 5.08)
No
Case/Total	152/414	633/1 732	419/934
HR	1 (reference)	1.09 (0.81, 1.32)	1.57 (1.28, 1.93)
Dyslipidemia				0.085
Yes
Case/Total	31/54	129/192	62/79
HR	1 (reference)	1.43 (0.96, 2.15)	2.58 (1.63, 4.09)
No
Case/Total	135/390	578/1 647	397/917
HR	1 (reference)	1.10 (0.91, 1.34)	1.55 (1.24, 1.93)

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