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Table 5 Receiver operating characteristic analysis for operational definitions of sarcopenia to predict impairment of ADL and IADL

From: Probable and confirmed sarcopenia are still better predictors of disability than sarcopenic obesity following ESPEN/EASO consensus steps

 

Impairment ADL

Impairment IADL

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

ROC AUC* (95% CI), significance (p)

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

ROC AUC* (95% CI), significance (p)

Probable sarcopenia

63.5

47.8

54.4

56.7

0.554 (0.499–0.610), 0.6

83.6

46.4

21.5

94.2

0.650 (0.582–0.718) < 0.001

Confirmed sarcopenia/W

22.2

84.9

59.2

52.4

0.535 (0.479–0.591) 0.22

36

84.4

29

88.3

0.603 (0.520–0.685) 0.01

Confirmed sarcopenia/BMI

35

78.1

61.2

54.8

0.565 (0.509–0.621), 0.02

57.4

76.7

30.2

91.1

0.670 (0.592–0.748)

< 0.001

Confirmed sarcopenia/H2

0

99.5

0

50

0.498 (0.441–0.554) 0.932

0

99.7

0

85.1

0.499 (0.420–0.577)

> 0.5

Sarcopenic obesity/W&BMI**

7.4

93.7

53.6

50.5

0.505 (0.449–0.561) 0.86

11.5

94

25

85.8

0.527 (0.446–0.608)

0.5

Obesity

41.4

68.3

56.4

54.1

0.548 (0.493–0.604) 0.09

49.2

65.7

20.1

88

0.574 (0.495–0.654)

0.06

  1. *AUC indicates area under the ROC curve
  2. ** Individuals who had SO according to calculation adjusted by weight (6.9%) were the same patients according to calculation adjusted by BMI (6.9%). For this reason, it is shown with the same line on the ROC curve and expressed as ‘Sarcopenic obesity/W&BMI’
  3. PPV: Positive predictive value, NPV: Negative predictive value, ADL: Activities of Daily Living, ROC: Receiver operating curve, AUC: Area under curve, BMI: body mass index, W: weight, H2: height square
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BMC Geriatrics

ISSN: 1471-2318

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