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Table 1 Baseline characteristics according to RAR quartiles

From: Red blood cell distribution width to albumin ratio (RAR) is associated with low cognitive performance in American older adults: NHANES 2011–2014

Characteristics

Quartiles of RAR

P-value

Overall

Q1(< 2.95)

Q2(2.95–3.16)

Q3(3.16–3.40)

Q4(> 3.40)

N (%)

2765

605

654

696

810

 

Age, years, mean (SD)

69.19(6.64)

67.70(6.11)

68.90(6.64)

69.80(6.63)

70.36(6.87)

< 0.001

Gender, n (%)

     

0.018

 Male

1357(46.2)

310(46.0)

347(52.4)

335(43.8)

365(42.2)

 

 Female

1408(53.8)

295(54.0)

307(47.6)

361(56.2)

445(57.8)

 

Race, n (%)

     

< 0.001

 Mexican American

244(3.4)

64(3.5)

73(4.0)

46(2.5)

61(3.3)

 

 Non-Hispanic White

1351(80.3)

293(82.5)

335(82.5)

359(81.8)

364(74.2)

 

 Non-Hispanic Black

628(7.9)

79(3.4)

113(5.2)

165(8.4)

271(14.8)

 

 Other

542(8.4)

169(10.6)

133(8.2)

126(7.3)

114(7.7)

 

Education, n (%)

     

0.005

 Less than high school

689(15.7)

130(10.8)

163(15.3)

169(16.6)

227(20.0)

 

 High school grad or equivalent

658(22.3)

134(23.5)

146(19.3)

165(20.8)

213(25.8)

 

 Some college or above

1418(62.0)

341(65.8)

345(65.3)

362(62.6)

370(54.2)

 

Marital, n (%)

     

< 0.001

 Married/Living with partner

1604(65.0)

382(70.4)

419(69.9)

399(64.2)

404(55.3)

 

 Widowed/Divorced/Separated

1001(30.6)

182(24.9)

203(26.5)

261(31.8)

355(39.3)

 

 Never married

160(4.4)

41(4.7)

32(3.6)

36(4.0)

51(5.4)

 

PIR, n (%)

     

< 0.001

 Low

841(18.1)

167(15.5)

186(13.9)

206(18.1)

282(25.2)

 

 Moderate

1043(37.4)

192(31.0)

251(37.8)

278(39.9)

322(40.9)

 

 High

881(44.4)

246(53.6)

217(48.3)

212(42.0)

206(33.8)

 

BMI (kg/m2), n (%)

     

< 0.001

 Normal/Underweight

758(26.8)

206(34.5)

197(27.3)

180(24.6)

175(20.8)

 

 Overweight

978(36.3)

255(41.9)

247(40.0)

247(34.9)

229(28.4)

 

 Obese

1029(36.9)

144(23.7)

210(32.7)

269(40.6)

406(50.7)

 

WC, (cm), mean (SD)

102.50(14.71)

97.91(13.00)

101.42(13.00)

103.51(14.87)

107.17(16.23)

< 0.001

HDL-C, mmol/L, mean (SD)

55.57(16.74)

58.83(18.53)

55.92(16.35)

54.10(15.59)

53.41(15.84)

0.001

Cr, mg/dL, mean (SD)

0.99(0.58)

0.91(0.23)

0.97(0.31)

0.97(0.33)

1.14(1.04)

< 0.001

UA, mg/dL, mean (SD)

5.61(1.43)

5.50(1.38)

5.65(1.42)

5.57(1.38)

5.73(1.53)

0.281

GGT, U/L, mean (SD)

25.56(30.50)

24.57(24.16)

24.48(25.53)

24.27(19.92)

28.93(45.61)

0.219

Hemoglobin, g/dL, mean (SD)

13.97(1.37)

14.27(1.24)

14.26(1.16)

14.02(1.28)

13.30(1.56)

< 0.001

HbA1c, %, mean (SD)

5.94(0.96)

5.74(0.74)

5.87(0.89)

5.97(0.91)

6.18(1.18)

< 0.001

Smoking status, n (%)

     

0.400

 Never

1364(49.9)

310(49.9)

329(52.0)

339(50.2)

386(47.5)

 

 Former

1042(38.9)

240(40.2)

236(36.4)

271(40.3)

295(38.6)

 

 Current

359(11.2)

55(10.0)

89(11.6)

86(9.4)

129(13.9)

 

Drinking status, n (%)

     

0.008

 Yes

1893(72.9)

444(78.3)

458(75.4)

478(71.2)

513(66.6)

 

 No

872(27.1)

161(21.7)

196(24.6)

218(28.8)

297(33.4)

 

Physical activity, n (%)

     

< 0.001

 Yes

1332(51.3)

348(62.6)

355(56.3)

324(47.0)

305(39.2)

 

 No

1433(48.7)

257(37.4)

299(43.7)

372(53.0)

505(60.8)

 

Hypertension, n (%)

     

0.068

 Yes

2210(77.0)

460(74.4)

515(75.5)

548(75.9)

687(82.3)

 

 No

555(23.0)

145(25.6)

139(24.5)

148(24.1)

123(17.7)

 

Hyperlipidemia, n (%)

     

0.232

 Yes

2345(85.8)

528(87.1)

556(86.1)

596(87.6)

665(82.3)

 

 No

420(14.2)

77(12.9)

98(13.9)

100(12.4)

145(17.7)

 

DM, n (%)

     

< 0.001

 Yes

903(26.5)

150(17.2)

200(24.8)

234(30.0)

319(33.9)

 

 No

1862(73.5)

455(82.8)

454(75.2)

462(70.0)

491(66.1)

 

CERAD-WL, (mean (SD)

25.99(6.39)

26.41(6.26)

26.46(6.49)

26.04(6.00)

25.04(6.70)

0.018

DSST, (mean (SD)

52.21(16.73)

57.06(16.60)

53.32(16.07)

51.64(15.88)

46.80(16.78)

< 0.001

AFT, (mean (SD)

18.08(5.64)

18.97(5.45)

18.71(5.79)

18.04(5.52)

16.61(5.48)

< 0.001

  1. The data are presented as the mean (SD) or n (%). All estimates were obtained from complex survey designs, analysis of variance or χ2 tests where appropriate. PIR poverty income ratio, BMI body mass index, WC waist circumference, HDL-C high density lipoprotein cholesterol, Cr creatinine, UA uric acid, GGT gamma-glutamyl transferase, HbA1c hemoglobin A1c, DM diabetes mellitus, RAR The red blood cell distribution width to albumin ratio, CERAD Consortium to Establish a Registry for Alzheimer’s Disease-Word Learning subtest, DSST Digit Symbol Substitution Test, AFT Animal Fluency Test, SD standard deviation