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Table 3 Determinants of clinically significant potential drug-drug interactions across the categories of socio-demographic and other background characteristics in Asmara, Eritrea, 2023

From: Inappropriate medication prescribing, polypharmacy, potential drug-drug interactions and medication regimen complexity in older adults attending three referral hospitals in Asmara, Eritrea: a cross-sectional study

Variable

Category

Bivariate analysis

Multivariable analysis

COR (95% CI)

P-value

AOR (95% CI)

P-value

Age

-

0.98 (0.95, 1.01)

0.121

-

-

Sex

Male

1.22 (0.82, 1.81)

0.338

-

-

Female

Ref

-

-

-

Presence of chronic illness

Yes

6.21 (3.33, 11.59)

 < 0.001

7.58 (3.73, 15.39)

 < 0.001

No

Ref

-

Ref

-

Prescriber qualification

GP

Ref

-

-

-

Nurse practitioner

0.30 (0.08, 1.12)

0.074

-

-

GP intern

0.45 (0.08, 2.48)

0.359

-

-

MRCI Score

-

1.18 (1.11, 1.26)

 < 0.001

1.08 (0.99, 1.17)

0.094

Number of drugs prescribed

-

3.23 (2.37, 4.40)

 < 0.001

2.80 (1.91, 4.10)

 < 0.001

  1. AOR Adjusted Odds Ratio, COR Crude Odds Ratio, GP General Practitioner, MRCI Medication Regimen Complexity Index, Ref Reference