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Table 3 Stratified analyses of the associations between dietary live microbe intake and the prevalence of frailty among older adults in NHANES 1999–2018

From: Dietary intake of live microbes and its association with frailty in older adults: a NHANES analysis (1999–2018)

Subgroups

N

Category of MedHi*

Pinteraction

Low

Medium

High

Sex, %

    

0.363

 Female

7735

1 [Reference]

0.810(0.704,0.931)

0.836(0.685,1.020)

 

 Male

7444

1 [Reference]

0.839(0.734,0.959)

0.745(0.620,0.895)

Race, %

    

0.804

 Non-Hispanic White

8038

1 [Reference]

0.828(0.730,0.939)

0.781(0.659,0.925)

 

 Non-Hispanic Black

2893

1 [Reference]

0.785(0.647,0.952)

0.787(0.584,1.061)

 Other

4248

1 [Reference]

0.883(0.724,1.077)

0.884(0.643,1.213)

Marital status, %

    

0.996

 Married/living with partner

8940

1 [Reference]

0.836(0.712,0.982)

0.769(0.624,0.946)

 

 Single/divorced/widowed

6239

1 [Reference]

0.821(0.714,0.944)

0.790(0.654,0.955)

 

Education level, %

    

0.097

 Below high school

4975

1 [Reference]

0.814(0.687,0.964)

0.959(0.729,1.260)

 

 High school

3642

1 [Reference]

0.909(0.746,1.107)

0.706(0.541,0.922)

 

 Above high school

6562

1 [Reference]

0.769(0.651,0.909)

0.755(0.609,0.936)

 

Family PIR, %

    

0.419

 ≤ 1.0

2561

1 [Reference]

1.014(0.818,1.257)

0.982(0.685,1.408)

 

 1.1–3.0

7279

1 [Reference]

0.804(0.686,0.943)

0.708(0.557,0.900)

 > 3.0

5339

1 [Reference]

0.789(0.630,0.989)

0.827(0.643,1.064)

Smoking status, %

    

0.594

 Never smoker

7330

1 [Reference]

0.767(0.655,0.898)

0.745(0.601,0.923)

 

 Former smoker

5974

1 [Reference]

0.908(0.773,1.068)

0.784(0.634,0.969)

 

 Current smoker

1875

1 [Reference]

0.737(0.544,1.000)

0.893(0.582,1.372)

 

Drinking status, %

    

0.176

 Nondrinker

4735

1 [Reference]

0.881(0.744,1.043)

0.877(0.699,1.102)

 

 Low-to-moderate drinker

9414

1 [Reference]

0.774(0.678,0.884)

0.716(0.605,0.846)

 

 Heavy drinker

1030

1 [Reference]

1.134(0.786,1.634)

1.133(0.668,1.922)

 

HEI, %

    

0.800

 Quartile 1

3795

1 [Reference]

0.791(0.645,0.969)

0.822(0.625,1.081)

 

 Quartile 2

3795

1 [Reference]

0.892(0.735,1.081)

0.705(0.535,0.928)

 

 Quartile 3

3794

1 [Reference]

0.808(0.653,0.999)

0.760(0.574,1.006)

 

 Quartile 4

3795

1 [Reference]

0.801(0.608,1.056)

0.837(0.608,1.153)

 
  1. Analyses were adjusted for covariates age (continous), sex (male or female), race/ethnicity (Non-Hispanic White, Non-Hispanic Black or Other), marital status (married/living with partner, or single/divorced/widowed), education level (below high school, high school, or above high school), family PIR (≤ 1.0, 1.1–3.0, or > 3.0), drinking status (nondrinker, former drinker, or current drinker), smoking status (never smoker, former smoker, or current smoker), and HEI (in quartiles) when they were not the strata variables
  2. * Participants were also classified into three different groups considering the general intake of foods with varying contents of microbe: low (all foods consumed were Low); moderate (any foods consumed were Medium but not High); and high (any foods consumed were High)