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Table 2 Correlation analysis of ALT related indicators with measures of Sarcopenia

From: Serum ALT activity and its isoenzymes as potential biomarkers for diagnosis of Sarcopenia in older adults: a retrospective, cross-sectional study

 

ALT activity

(n = 653)

ALT1

(n = 109)

ALT2

(n = 109)

ALT1/ALT2

(n = 109)

r

p

r

p

r

p

r

p

HGS

0.218

< 0.001

-0.072

0.551

-0.090

0.478

-0.253

0.029

Gait Speed

0.218

< 0.001

-0.166

0.226

-0.131

0.335

-0.203

0.110

FTSST

-0.242

< 0.001

0.073

0.557

-0.055

0.662

0.367

0.003

ASMI

0.213

< 0.001

0.001

0.995

0.037

0.774

-0.057

0.655

  1. ALT activity: ALT activity tertiles (Tertile 1 ≤ 13.80 U/L, Tertile 2 13.81–19.80 U/L, Tertile 3 ≥ 19.81 U/L); ALT1: ALT1 tertiles (Tertile 1 ≤ 17.17 ng/ml, Tertile 2 17.18–32.83 ng/ml, Tertile 3 ≥ 32.84 ng/ml); ALT2: ALT2 tertiles (Tertile 1 ≤ 14.79 ng/ml, Tertile 2 14.80-30.23 ng/ml, Tertile 3 ≥ 30.24 ng/ml); ALT1/ALT2: ALT1/ALT2 ratio tertiles (Tertile 1 ≤ 0.99, Tertile 2 1.00-1.22, Tertile 3 ≥ 1.23). Abbreviations: ALT, alanine aminotransferase; HGS, hand grip strength; FTSST, five times sit-to-stand test; ASMI, appendicular skeletal muscle mass index; BMI, body mass index