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Table 1 Clinical characteristics between non-sarcopenia and Sarcopenia in older adults

From: Serum ALT activity and its isoenzymes as potential biomarkers for diagnosis of Sarcopenia in older adults: a retrospective, cross-sectional study

 

Total population (N = 653)

Subpopulation (N = 109)

Characteristics

Non-sarcopenia

N = 373

Sarcopenia

N = 280

p value

Non-sarcopenia

N = 51

Sarcopenia

N = 58

p value

Age, years

65.0 (8.0)

68.5 (9.0)

< 0.001

64.3 ± 5.5

69.8 ± 7.2

< 0.001

Female (n, %)

272, 72.9

202, 72.1

0.825

46, 90.2

51, 87.9

0.706

BMI, kg/m2

23.8 (4.8)

23.0 (4.4)

0.016

24.7 ± 3.8

23.3 ± 2.8

0.024

Diabetes (n, %)

214, 57.4

171, 61.1

0.342

18, 35.3

28, 48.3

0.171

Osteoporosis (n, %)

193, 51.7

157, 56.1

0.272

40, 78.4

47, 81.0

0.735

ASMI, kg/m2

5.27 (1.18)

4.80 (0.90)

< 0.001

5.13 ± 0.79

4.60 ± 0.51

< 0.001

HGS, kg

25.4 (10.2)

21.0 (8.1)

< 0.001

23.0 (6.4)

21.0 (8.4)

0.001

Gait Speed, m/s

1.20 (0.23)

0.93 (0.29)

< 0.001

1.17 (0.18)

0.89 (0.24)

< 0.001

FTSST, s

9.53 (2.37)

13.31 (7.14)

< 0.001

9.84 (2.03)

14.26 (15.91)

< 0.001

ALT, U/L

17.9 (11.6)

14.6 (8.3)

< 0.001

17.9 (7.5)

14.5 (9.2)

0.003

ALT1, ng/ml

/

/

/

20.4 (19.3)

24.5 (28.2)

0.229

ALT2, ng/ml

/

/

/

21.8 (23.0)

19.1 (26.0)

0.969

ALT1/ALT2

/

/

/

1.05 (0.37)

1.21 (0.32)

0.001

AST, U/L

17.9 (7.2)

17.4 (5.8)

0.014

18.4 (6.2)

17.3 (5.9)

0.153

Creatinine, umol/L

64.0 (15.0)

64.0 (19.8)

0.428

61.0 (13.0)

62.0 (17.3)

0.590

Uric Acid, umol/L

305 (101)

308 (124)

0.301

307 (51)

300 (128)

0.855

  1. Data are presented as mean ± SD or median (interquartile range) or n (%). Abbreviations: BMI, body mass index; ASMI, appendicular skeletal muscle mass index; HGS, hand grip strength; FTSST, five times sit-to-stand test; ALT, alanine aminotransferase; AST, aspartate aminotransferase