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Table 3 Logistic regression analyses for secondary outcomes

From: Association between edaravone use and activities of daily living in older patients with atherothrombotic stroke: an observational study using Japanese real-world data

  

Crude

  

Adjusted

 
 

OR

95% CI

P value

OR

95% CI

P value

Dependent variable: BI at discharge ≥ 90

 Edaravone use

1.00

0.89–1.13

0.962

0.91

0.77–1.08

0.274

 Age, per 10 years

0.37

0.34–0.40

<0.001

0.43

0.38–0.47

<0.001

 Male

1.97

1.75–2.20

<0.001

1.56

1.34–1.83

<0.001

 BMI < 20kg/m2

0.49

0.42–0.57

<0.001

0.59

0.49–0.72

<0.001

JCS at admission

 0

reference

  

reference

  

 1–3

0.30

0.27–0.34

<0.001

0.35

0.30–0.41

<0.001

 10–30

0.10

0.07–0.13

<0.001

0.13

0.09–0.19

<0.001

 100–300

0.04

0.02–0.11

<0.001

0.07

0.02–0.22

<0.001

 eGFR < 60 mL/min /1.73m2 

0.71

0.62–0.81

<0.001

0.90

0.77–1.06

0.210

 HTN medication at onset

0.83

0.74–0.94

0.004

0.86

0.73–1.02

0.084

 Intravenous drug usea

0.70

0.60–0.83

<0.001

0.72

0.57–0.89

0.003

Dependent variable: mRS at discharge 0–2

 Edaravone use

1.00

0.90–1.13

0.948

0.91

0.78–1.06

0.215

 Age, per 10 years

0.46

0.42–0.49

<0.001

0.56

0.51–0.61

<0.001

 Male

1.69

1.52–1.89

<0.001

1.30

1.12–1.50

<0.001

 BMI < 20 kg/m2

0.55

0.48–0.64

<0.001

0.69

0.58–0.83

<0.001

JCS at admission

 0

reference

  

reference

  

 1–3

0.32

0.28–0.35

<0.001

0.39

0.33–0.45

<0.001

 10–30

0.10

0.08–0.14

<0.001

0.16

0.11–0.22

<0.001

 100–300

0.04

0.02–0.09

<0.001

0.06

0.02–0.15

<0.001

 eGFR < 60 mL/min /1.73m2 

0.72

0.64–0.82

<0.001

0.89

0.77–1.03

0.119

 HTN medication at onset

0.82

0.73–0.92

0.001

0.83

0.71–0.97

0.016

  1. BI Barthel Index, BMI Body mass index, CI Confidence interval, eGFR Estimated glomerular filtration rate, HTN Hypertension, JCS Japan coma scale, mRS Modified Rankin Scale, OR Odds ratio
  2. aAlteplase, argartoban or ozagrel