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Table 2 Logistic regression analysis for the primary outcome. Dependent variable: improvement of ADL

From: Association between edaravone use and activities of daily living in older patients with atherothrombotic stroke: an observational study using Japanese real-world data

  

Crude

  

Adjusted

 

Independent variable

OR

95% CI

P value

OR

95% CI

P value

Edaravone use

1.21

1.07–1.36

0.002

1.18

1.01–1.37

0.032

Age, per 10 years

0.68

0.63–0.73

 < 0.001

0.72

0.65–0.79

< 0.001

Male

1.33

1.18–1.49

 < 0.001

1.18

1.02–1.36

0.025

BMI < 20 kg/m2

0.80

0.69–0.92

0.002

0.93

0.79–1.11

0.439

JCS at admission

0

reference

reference

1–3

0.99

0.88–1.11

0.847

1.04

0.89–1.20

0.623

10–30

0.55

0.44–0.69

 < 0.001

0.63

0.48–0.83

0.001

100–300

0.32

0.20–0.51

 < 0.001

0.38

0.21–0.67

0.001

eGFR < 60 mL/min /1.73m2

0.92

0.81–1.06

0.243

1.08

0.93–1.25

0.304

HTN medication at onset

0.86

0.76–0.98

0.019

0.86

0.74–1.01

0.058

Intravenous drug usea

1.08

0.92–1.28

0.338

0.94

0.77–1.15

0.527

  1. BMI Body mass index, CI Confidence interval, eGFR estimated glomerular filtration rate, HTN Hypertension, JCS Japan Coma Scale, OR odds ratio
  2. aAlteplase, argatroban or ozagrel