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Table 1 Baseline characteristic of the study population by cardiovascular health (CVH) status

From: Association between life’s essential 8 and cognitive impairment in older patients: results from NHANES 2011–2014

Characteristic

Total

(n = 2415)

Low CVH (0–49)

(n = 277)

Moderate CVH (50–79)

(n = 1867)

High CVH (80–100)

(n = 271)

P value

Age, y

69.44 ± 6.77

68.55 ± 6.52

69.53 ± 6.79

69.74 ± 6.79

0.057

Sex, n (%)

    

0.504

Male

1213 (50.23)

130 (46.93)

945 (50.62)

138 (50.92)

 

Female

1202 (49.77)

147 (53.07)

922 (49.38)

133 (49.08)

 

BMI

29.06 ± 6.32

33.73 ± 7.53

28.95 ± 5.95

24.64 ± 3.36

< 0.001

Race, n (%)

    

< 0.001

Mexican American

199 (8.24)

28 (10.11)

155 (8.30)

16 (5.90)

 

Other Hispanic

252 (10.43)

29 (10.47)

207 (11.09)

16 (5.90)

 

Non-Hispanic White

1207 (49.98)

116 (41.88)

931 (49.87)

160 (59.04)

 

Non-Hispanic Black

549 (22.73)

96 (34.66)

415 (22.23)

38 (14.02)

 

Other Race - Including Multi- Racial

208 (8.61)

8 (2.89)

159 (8.52)

41 (15.13)

 

Marital status, n (%)

    

< 0.001

Married/Living with Partner

1424 (58.96)

138 (49.82)

1099 (58.86)

187 (69.00)

 

Never married

142 (5.88)

21 (7.58)

107 (5.73)

14 (5.17)

 

Widowed/Divorced/ Separated

849 (35.16)

118 (42.60)

661 (35.40)

70 (25.83)

 

Education levels, n (%)

    

< 0.001

< High school

596 (24.68)

88 (31.77)

477 (25.55)

31 (11.44)

 

High school

566 (23.44)

79 (28.52)

448 (24.00)

39 (14.39)

 

College or above

1253 (51.88)

110 (39.71)

942 (50.46)

201 (74.17)

 

Income status

    

< 0.001

High income

691 (28.61)

115 (41.52)

532 (28.49)

44 (16.24)

 

Middle income

923 (38.22)

102 (36.82)

741 (39.69)

80 (29.52)

 

Low income

801 (33.17)

60 (21.66)

594 (31.82)

147 (54.24)

 

Smoking, n (%)

1229 (50.89)

197 (71.12)

948 (50.78)

84 (31.00)

< 0.001

Drinking, n (%)

1669 (69.11)

192 (69.31)

1284 (68.77)

193 (71.22)

0.716

Sleep Disorder, n (%)

715 (29.61)

140 (50.54)

541 (28.98)

34 (12.55)

< 0.001

Depression, n (%)

231 (9.57)

42 (15.16)

179 (9.59)

10 (3.69)

< 0.001

Stroke, n (%)

160 (6.63)

23 (8.30)

126 (6.75)

11 (4.06)

0.123

Cardiovascular diseases, n (%)

433 (17.93)

65 (23.47)

333 (17.84)

35 (12.92)

0.005

Hypertension, n (%)

1480 (61.28)

209 (75.45)

1171 (62.72)

100 (36.90)

< 0.001

Triglycerides (mg/dL)

124.74 ± 54.00

156.55 ± 66.64

124.83 ± 51.38

91.59 ± 33.89

< 0.001

Cholesterol (mg/dL)

191.53 ± 43.00

203.92 ± 53.96

190.28 ± 42.00

187.53 ± 34.32

< 0.001

WBC

6.98 ± 2.52

8.00 ± 3.51

6.95 ± 2.40

6.15 ± 1.62

< 0.001

RBC

4.50 ± 0.50

4.60 ± 0.56

4.49 ± 0.49

4.44 ± 0.47

0.002

LE 8

65.16 ± 12.05

44.53 ± 4.54

65.43 ± 8.13

84.39 ± 3.57

< 0.001

CERAD, n (%)

529 (21.9)

62 (22.38)

432 (23.14)

35 (12.92)

< 0.001

AST, n (%)

467 (19.34)

65 (23.47)

356 (19.07)

46 (16.97)

0.130

DDST, n (%)

549 (22.73)

89 (32.13)

441 (23.62)

19 (7.01)

< 0.001

Global cognitive impairment, n (%)

998 (41.33)

138 (49.82)

782 (41.89)

78 (28.78)

< 0.001

  1. WBC: White blood cells; RBC: Red blood cells; The Consortium to Establish a Registry for Alzheimer’s Disease (CERAD); Digit Symbol Substitution Test (DSST); Animal Fluency test (AFT);
  2. Continuous variables were shown in mean (SD) and categorical variables were shown in percentages