Table 1 Characteristics of the population according to SIgA-S1 (“induced” vs.“non-induced” SIgA-S1)

Aged. years

88.0 [84.0–93.0]

88.0 [84.0–93.0]

88.0 [83.0–93.0]

0.929

Aged by groups. years

 70–75

20 (6.5)

16 (5.8)

4 (12.9)

0.671

 76–80

34 (11.1)

31 (11.3)

3 (9.7)

 81–85

52 (17.0)

48 (17.5)

4 (12.9)

 86–90

89 (29.1)

81 (29.6)

8 (25.8)

 > 90

110 (36.7)

98 (35.8)

12 (38.7)

Sex

 Male

78 (25.5)

73 (26.6)

5 (16.1)

0.203

 Female

227 (74.4)

201 (73.4)

26 (83.9)

Comprehensive geriatric assessment

 Clinical Frailty Scale (CFS)

7.0 [5–7]

7.0 [5.0–7.0]

6.0 [4.5-7.0]

0.230

 Barthel Index

38[15–71]

36.0 [15.0–70.0]

48.5 [15.5–78.0]

0.369

 Dementia

90 (33.3)

84 (34.4)

6 (23.1)

0.243

  GDS grade

4.0 [3.0–6.0]

4.0 [3.0–6.0]

4.0 [2.0–5.0]

0.344

 Comorbidities per patient

2.0 [1.0–3.0]

2.0 [1.0–3.0]

1.0 [1.0–2.0]

0.044

 Most frequent comorbidities

  Hypertension

189 (62.5)

173 (63.8)

16 (51.6)

0.183

  Cirrhosis

6 (1.99)

5 (1.8)

1 (3.2)

0.481

  Diabetes

69 (22.85)

65 (24.,0)

4 (12.9)

0.164

  Chronic Renal Disease

33 (10.93)

32 (11.8)

1 (3.2)

0.223

  Obesity

24 (7.9)

21 (7.7)

28 (90.3)

0.723

  Chronic Neurological Disease

77 (25.5)

71 (26.2)

6 (19.4)

0.408

  Heart failure

47 (15.5)

42 (15.5)

5 (16.1)

1.00

  Chronic Inflammatory Disease

15 (4.97)

14 (5.2)

1 (3.2)

1.00

  Ischemic heart disease

28 (9.27)

27 (10.0)

1 (3.2)

0.332

  Solid neoplasm

38 (12.6)

35 (13.0)

3 (9.7)

0.779

  Asthma

6 (1.9)

5 (1.8)

1 (3.2)

0.481

  Hematological neoplasm

6 (1.9)

6 (2.2)

0 (0.0)

1.00

  COPD

26 (8.6)

22 (8.1)

4 (12.9)

0.323

  Sleep apnea syndrome

7 (2.3)

7 (2.6)

0 (0.0)

1.00

  Malnutrition

25 (8.2)

23 (8.5)

2 (6.5)

1.00

Symptoms

 Fever

75 (25.7)

69 (25.8)

6 (19.4)

0.431

 Arthromyalgia

11 (3.69)

9 (3.4)

2 (6.5)

0.320

 Headache

40 (13.4)

36 (13.5)

4 (12.9)

1.00

 Symptoms of upper respiratory tract

69 (23.1)

67 (25.1)

2 (6.5)

0.020

 Dyspnea

39 (13.0)

35 (13.1)

4 (12.9)

1.00

 Epileptic seizures

6 (2.0)

6 (2.2)

0 (0.0)

1.00

 Chest pain

9 (3.0)

8 (3.0)

1 (3.2)

1.00

 Abdominal pain

9 (3.0)

9 (3.4)

0 (0.0)

0.605

 Cough

75 (25.1)

71 (26.6)

4 (12.9)

0.096

 Vomiting

39 (13.0)

37 (13.9)

2 (6.5)

0.397

 Diarrhea

35 (11.74)

33 (12.4)

2 (6.5)

0.554

 Hemoptysis

0 (0.0)

0 (0.0)

0 (0.0)

NA

 Ageusia

0 (0.0)

0 (0.0)

0 (0.0)

 Anosmia

0 (0.0)

0 (0.0)

0 (0.0)

 Alteration of the level of consciousness

16 (5.3)

15 (5.6)

1 (3.2)

1.00

 Refusal of ingestion

37 (12.4)

35 (13.1)

2 (6.5)

0.395

Number of symptom per patient

2.0 [1.0–4.0]

2.0 [1.0–4.0]

3.0 [2.0–4.0]

0.215

Number of patient with any symptom

170 (57)

161 (60.3)

9 (29.0)

< 0.001

 Numer of days with symptoms

1.0 [0.0–10.0]

1.5 [0.0–10.0]

1.0 [0.0–10.0]

0.797

Vital Signs

 Temperature (Celsius)

36.6 [36.1–37.3]

36.4 [36.1–37.2]

36.4 [36.2–37.7]

0.586

 Systolic blodd pressure (mmHg)

121.0 [110–132]

120.5 [110–132]

128.5 [119.0-143.5]

0.113

 Heart rate (bpm)

74.0 [65.0–81.0]

74.0 [65.0–81.0]

75.0 [72.0–81.0]

0.506

 Basal saturation (%)

91.325 [89.2–95.0]

92.0 [90.0–95.0]

93.0 [88.0–95.0]

0.713

Positive PCR SARS-CoV-2

46 (15.1)

42 (15.3)

4 (12.9)

1.00

 Cycles threshold

37.1 [36.5–38.5]

37.2 [36.8–38]

36.8 [34.9–38.6]

0.253

Severe Case*

81 (33.9)

75 (27.4)

6 (19.4)

0.338

Mortality at 30 days

8.0 (2.6)

8 (2.9)

0 (0.0)

1.00

Reinfection at 90 days

6 (5.61)

6 (6.2)

0 (0.0)

1.00